Pain in the newborn brain: a neural signature
نویسندگان
چکیده
منابع مشابه
The epigenetic signature of chronic pain in the mouse brain
Background Peripheral nerve injury can be accompanied by long-term pain-related manifestations, such as affective and cognitive disturbances, suggesting the involvement of supraspinal mechanisms. One particular region of interest is the prefrontal cortex (PFC), an area implicated in depression, anxiety and cognitive impairment, all of which are frequently associated with chronic pain [1-4]. Cli...
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To study the patterns of supraspinal pain processing in neonates, we hypothesized that acute pain causes haemodynamic changes associated with activation of the primary somatosensory cortex. Forty preterm neonates at 28-36 weeks of gestation (mean=32.0) and at 25-42 h (mean=30.7) of age were studied following standardized tactile (skin disinfection) and painful (venipuncture) stimuli. Changes in...
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O the last several decades, there has been an increased awareness of the importance of assessing and managing pain in hospitalized newborns. One only has to spend time in the NICU to observe how frequently newborns encounter postoperative, procedural, and disease-related pain throughout their hospital stay. Although neonates cannot specifically communicate pain, they do display physiologic and ...
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Recent scientific studies have added more and more consistent evidence that the newborn, even if preterm, is very sensitive to the nociceptive stimulus. The baby responds with a well known physiological, metabolic and hormonal reaction, that, if repeated, may lead to short and medium term negative effects on the newborn. This vulnerability to painful stimulus, especially in preterm infants, can...
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ژورنال
عنوان ژورنال: The Lancet Digital Health
سال: 2020
ISSN: 2589-7500
DOI: 10.1016/s2589-7500(20)30191-6